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Western Caribbean

Margaritaville at Sea Cruises to Grand Cayman

Seven Mile Beach, Stingray City, and some of the clearest water in the Caribbean. Grand Cayman features on the longer Western Caribbean Margaritaville at Sea itineraries.

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14 itineraries visit Grand Cayman

Sailings that call on Grand Cayman

Margaritaville at Sea Islander7 nights

Margaritaville at Sea Islander

7-Night Key West & Western Caribbean

Departs Tampa, FL

  • Key West
  • Roatan
  • Belize
  • Cozumel
  • Grand Cayman
  • Montego Bay
  • Progreso
  • Ocho Rios

10 departures from Aug 22, 2026

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Margaritaville at Sea Islander7 nights

Margaritaville at Sea Islander

7-Night Jamaica & Western Caribbean

Departs Tampa, FL

  • Cozumel
  • Ocho Rios
  • Grand Cayman
  • Montego Bay

8 departures from Aug 29, 2026

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Margaritaville at Sea Islander10 nights

Margaritaville at Sea Islander

10-Night Aruba, Curacao & Caribbean

Departs Tampa, FL

  • Grand Cayman
  • Aruba
  • Curacao
  • Ocho Rios

1 departure from Sep 5, 2026

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Margaritaville at Sea Beachcomber7 nights

Margaritaville at Sea Beachcomber

7-Night Grand Cayman, Jamaica & Bahamas

Departs Miami, FL

  • Grand Cayman
  • Ocho Rios
  • Nassau

1 departure from Jan 23, 2027

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Margaritaville at Sea Beachcomber6 nights

Margaritaville at Sea Beachcomber

6-Night Key West & Western Caribbean

Departs Miami, FL

  • Key West
  • Montego Bay
  • Grand Cayman

1 departure from Jan 30, 2027

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Margaritaville at Sea Islander8 nights

Margaritaville at Sea Islander

8-Night Jamaica & Western Caribbean

Departs Tampa, FL

  • Cozumel
  • Belize
  • Montego Bay
  • Grand Cayman

1 departure from Jan 30, 2027

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Margaritaville at Sea Beachcomber7 nights

Margaritaville at Sea Beachcomber

7-Night Key West, Bahamas & Western Caribbean

Departs Miami, FL

  • Key West
  • Grand Cayman
  • Ocho Rios
  • Nassau
  • Montego Bay

8 departures from Mar 27, 2027

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Margaritaville at Sea Beachcomber6 nights

Margaritaville at Sea Beachcomber

6-Night Bahamas & Western Caribbean

Departs Miami, FL

  • Grand Cayman
  • Ocho Rios
  • Grand Bahama

1 departure from Apr 10, 2027

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Margaritaville at Sea Beachcomber7 nights

Margaritaville at Sea Beachcomber

7-Night Dominican Republic & Western Caribbean

Departs Miami, FL

  • Puerto Plata
  • Ocho Rios
  • Grand Cayman

3 departures from May 1, 2027

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Margaritaville at Sea Beachcomber7 nights

Margaritaville at Sea Beachcomber

7-Night Key West & Western Caribbean

Departs Miami, FL

  • Key West
  • Grand Cayman
  • Ocho Rios

1 departure from Jun 26, 2027

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Margaritaville at Sea Beachcomber5 nights

Margaritaville at Sea Beachcomber

5-Night Key West & Western Caribbean

Departs Miami, FL

  • Key West
  • Grand Cayman

1 departure from Sep 13, 2027

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Margaritaville at Sea Islander10 nights

Margaritaville at Sea Islander

10-Night Southern & Western Caribbean

Departs Tampa, FL

  • Cabo Rojo
  • Aruba
  • Curacao
  • Montego Bay
  • Grand Cayman

1 departure from Sep 13, 2027

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Margaritaville at Sea Islander8 nights

Margaritaville at Sea Islander

8-Night Mexico & Western Caribbean

Departs Tampa, FL

  • Grand Cayman
  • Roatan
  • Belize
  • Cozumel

1 departure from Oct 9, 2027

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Margaritaville at Sea Islander5 nights

Margaritaville at Sea Islander

5-Night Key West & Cayman

Departs Tampa, FL

  • Key West
  • Grand Cayman

1 departure from Dec 23, 2027

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Sail to Grand Cayman for less

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